BPC-157 — dosage, half-life & reference guide

Healing & recovery peptide · also known as Body Protection Compound 157, BPC157

A peptide derived from a protective protein in your stomach. BPC-157 promotes the formation of new blood vessels and accelerates the repair of tendons, ligaments, muscles, and gut lining. Many people use it for injury recovery and digestive healing — it's one of the most widely used peptides in the community.

Commonly-researched dose ranges

BPC-157 is commonly researched at 200–500 mcg, once or twice daily, by SubQ injection, IM injection, Oral (less studied). These are reference ranges from the literature and community use, not a prescription.

Half-life

Estimated half-life: ~4 hours (SubQ). See how it accumulates in the half-life calculator.

Safety & interactions

A 2025 peer-reviewed review (McGuire et al., Curr Rev Musculoskelet Med, Univ. of Utah) confirms human evidence is limited to three tiny uncontrolled studies by a single investigator — ~16 knee patients, ~12 interstitial-cystitis patients, and 2 IV subjects (up to 20 mg, no adverse events) — with no controls and no long-term human data of any kind. Most safety data otherwise comes from rodent and dog studies, where it was well tolerated with no serious toxicity and a very short plasma half-life (~15 min in rats). Community use reports mostly transient injection-site reactions. Note the regulatory status: WADA-banned since 2022 (S0), and FDA Category 2 since September 2023 (insufficient safety evidence for compounding). A theoretical caution worth raising: its proangiogenic activity could in principle support unwanted tissue (e.g. tumor) growth — not observed in the small human data, but uncharacterized. Discuss with your clinician; this is not an approved drug and long-term human safety is unestablished.

Open the full BPC-157 guide (needs JavaScript). PepVault is a private research and tracking tool, not medical advice.