Cagrilintide dose guide

A peptide dosage chart, one peptide at a time: its dose range, how often it’s taken, a typical run and the units on your syringe. All 69 peptides in the PepVault library.

A community reference, not medical advice. Each range is what has been studied or is commonly run, never a dose for you.

Cagrilintide dosage

A long-acting version of amylin, the fullness hormone the pancreas releases alongside insulin, given as a weekly shot. On its own, its higher doses led to about 10–12% weight loss in trials; the crowd mostly runs it beside a GLP-1 such as semaglutide, tirzepatide or retatrutide, the way Novo Nordisk pairs it with semaglutide in CagriSema. Commonly reported: feeling full sooner and portions shrinking, with nausea or constipation after step-ups and some injection-site reactions. It is not approved on its own.

Dose range
0.25–2.4 mg (research range). Studied in research — not a recommendation.
How often
Weekly
A typical run
Ongoing. Trials run it continuously: 26 weeks in phase 2, 68 weeks in phase 3. Community use is mostly as a weekly add-on to a GLP-1.
How it’s taken
Vial: SubQ injection
Evidence
Established: Clinical trials or FDA-approved use exists
Half-life
~1 week (measured in people: 159–195 hours in a phase 1b trial)

Cagrilintide on your syringe

With a 10 mg vial and 2 mL of water (5 mg in every mL), on a 0.5 mL (50-unit) U-100 insulin syringe: the low end, 0.25 mg, is 5 units; and the high end, 2.4 mg, is 48 units. 40 doses in the vial at the low end. All U-100: 100 units to the mL. A U-40 syringe reads differently.

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A community reference, not medical advice. Each range is what has been studied or is commonly run, never a dose for you.