NAD+ — dosage, half-life & reference guide

Longevity peptide · also known as Nicotinamide adenine dinucleotide, NAD, NAD plus

NAD+ is a coenzyme every cell needs to turn food into usable energy — and the same molecule your sirtuin "longevity" enzymes and DNA-repair machinery run on. Levels fall as you age, and supplementation aims to top the pool back up. Most human evidence is for the oral precursors (NMN and NR) that your body converts into NAD+; direct injectable NAD+ is popular in practice but thinner on controlled trials.

Commonly-researched dose ranges

NAD+ is commonly researched at 50–100 mg, daily or eod, by SubQ injection, IV infusion, Intranasal. These are reference ranges from the literature and community use, not a prescription.

Half-life

Estimated half-life: Minutes (rapidly metabolized). See how it accumulates in the half-life calculator.

Safety & interactions

Commonly reported effects: flushing, nausea if dosed too fast, injection site stinging, transient chest tightness (fast iv). Discuss with your clinician.

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