IGF-1 LR3 dose guide

IGF-1 LR3 dosage

IGF-1 is the growth factor your liver and muscles make when growth hormone arrives — the messenger that does much of GH's building work. IGF-1 LR3 is a lab-modified copy designed to slip past the proteins that normally hold IGF-1 in reserve, which makes it several times more potent in a dish and in rats, and also makes it clear faster. Commonly reported: fuller muscles and quicker recovery, hunger, and the shaky, sweaty, light-headed feeling of a blood-sugar dip within an hour or two of a dose. There are no human studies of it, and low blood sugar is the one documented risk of the class.

Dose range

20–50 mcg (research range). Studied in research — not a recommendation.

How often

Daily: Daily (community protocols: training days)

A typical run

3–6 weeks per community cycle. Community cycles commonly run 3 to 6 weeks with an equal or longer break, on the belief that the IGF-1 receptor downregulates; no study has tested that in people. The animal work that found it anabolic used continuous infusion from an implanted pump over 7 to 14 days; given as daily injections it worked much less well than by infusion, though it still beat plain IGF-1 on several measures (not on muscle loss in catabolic rats).

How it’s taken

Vial: SubQ injection

Evidence

Emerging: Primarily preclinical / limited human data

Half-life

Not measured in people: no human pharmacokinetic study of IGF-1 LR3 has been published. In rats it cleared from plasma about ten times faster than IGF-1 (Bastian 1993), because escaping the binding proteins is both what makes it potent and what lets it clear. The 20–30 hour figure repeated across community guides traces to one unreferenced sentence in the methods of a mouse atherosclerosis paper and has never been measured.

IGF-1 LR3 on your syringe

With a 5 mg vial and 2 mL of water (2.5 mg in every mL), on a 0.3 mL (30-unit) U-100 insulin syringe: the low end, 20 mcg, is under 1 unit; and the high end, 50 mcg, is 2 units. All U-100: 100 units to the mL. A U-40 syringe reads differently.

IGF-1 LR3 in the peptide libraryThe Dose Guide: every peptide

More growth hormone peptides

• Ipamorelin 200–300 mcg
• CJC-1295 with DAC 1–2 mg
• CJC-1295 no DAC 100–200 mcg
• Sermorelin 200–500 mcg
• Tesamorelin 1–2 mg
• GHRP-2 100–300 mcg
• GHRP-6 100–300 mcg
• Hexarelin 100–200 mcg
• MK-677 10–25 mg
• Fragment 176-191 250–500 mcg
• PEG-MGF 200–400 mcg
• Follistatin-344 100–200 mcg
• HGH 1–4 IU

A community reference, not medical advice. Each range is what has been studied or is commonly run, never a dose for you.