Follistatin-344 dose guide

Follistatin-344 dosage

Myostatin is the brake on muscle growth — the protein that explains double-muscled cattle when it is missing. Follistatin is the body's own brake-release: it binds myostatin, and activin A as well, and mice over-expressing it grow muscle like myostatin-knockout mice. Its human evidence comes from gene therapy rather than from the vial sold as a research peptide, and the one published human series on the injected peptide is eleven bodybuilders who developed a retinal problem after high single doses, which cleared on its own in those who injected once. Commonly reported: injection-site redness, sometimes mild fatigue, and plenty of people reporting nothing they can separate from training — unsurprising when only about half the products tested (9 of 17) contained any.

Dose range

100–200 mcg (research range). Studied in research — not a recommendation.

How often

Daily

A typical run

10–30 days per community cycle. Community cycles commonly run 10 to 30 days with 3 to 4 weeks off, on the reasoning that the peptide clears fast and the protein is expensive; none of that comes from a study. The human gene-therapy work is the opposite shape — a single intramuscular delivery meant to keep producing follistatin for years. The eye cases that give this compound its only human safety record clustered in people who injected a whole vial at once, and recurred in those who repeated it.

How it’s taken

Vial: SubQ injection

Evidence

Emerging: Primarily preclinical / limited human data

Half-life

Not measured in people: no human pharmacokinetic study of injected follistatin has been published. In rats, labelled follistatin given into a vein cleared in two phases, about 4 minutes then about 2 hours, and collected in the liver (Kogure 1996). Drug companies that tried to develop it found native follistatin cleared too fast to work as an injection and had to engineer around it. The 90-minute figure community guides quote has never been measured; the rat terminal value is about 131 minutes.

Follistatin-344 on your syringe

With a 5 mg vial and 3 mL of water (1.67 mg in every mL), on a 0.3 mL (30-unit) U-100 insulin syringe: the low end, 100 mcg, is 6 units; and the high end, 200 mcg, is 12 units. 50 doses in the vial at the low end. All U-100: 100 units to the mL. A U-40 syringe reads differently.

Follistatin-344 in the peptide libraryThe Dose Guide: every peptide

More growth hormone peptides

• Ipamorelin 200–300 mcg
• CJC-1295 with DAC 1–2 mg
• CJC-1295 no DAC 100–200 mcg
• Sermorelin 200–500 mcg
• Tesamorelin 1–2 mg
• GHRP-2 100–300 mcg
• GHRP-6 100–300 mcg
• Hexarelin 100–200 mcg
• MK-677 10–25 mg
• Fragment 176-191 250–500 mcg
• IGF-1 LR3 20–50 mcg
• PEG-MGF 200–400 mcg
• HGH 1–4 IU

A community reference, not medical advice. Each range is what has been studied or is commonly run, never a dose for you.