Oxytocin — dosage, half-life & reference guide

Metabolic & GLP-1 peptide · also known as OT, Love hormone, Oxytocin nasal

Best known as the "bonding hormone," oxytocin is a hypothalamic neuropeptide with broader effects than most people realize. Delivered as a nasal spray, it reduces appetite and food reward signaling, lowers stress, and has anti-inflammatory properties. Growing community use for appetite control alongside metabolic peptide protocols.

Commonly-researched dose ranges

Oxytocin is commonly researched at 10–40 IU, 1–2x daily or as needed, by Intranasal. These are reference ranges from the literature and community use, not a prescription.

Half-life

Estimated half-life: ~3 min IV; intranasal 30–60 min. See how it accumulates in the half-life calculator.

Safety & interactions

Commonly reported effects: mild headache, nausea at high doses, tolerance with frequent use. Discuss with your clinician.

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