NSI-189 — dosage, half-life & reference guide

Cognitive peptide · also known as NSI189, NSI 189 phosphate

A neurogenic compound that stimulates the growth of new neurons in the hippocampus — the brain region critical for memory and mood. NSI-189 went through Phase 2 clinical trials for major depressive disorder with promising cognitive results. Effects on mood and memory can persist for weeks after cycling off, suggesting lasting structural brain changes.

Commonly-researched dose ranges

NSI-189 is commonly researched at 40–80 mg, daily, split into 2 doses, by Oral. These are reference ranges from the literature and community use, not a prescription.

Half-life

Estimated half-life: Unknown; effects persist after cycling. See how it accumulates in the half-life calculator.

Safety & interactions

Commonly reported effects: headache, irritability at high doses, vivid dreams, initial anxiety increase. Discuss with your clinician.

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