Kisspeptin-10 — dosage, half-life & reference guide

Sexual health peptide · also known as KP-10, Kisspeptin, Metastin fragment

A hypothalamic neuropeptide that sits upstream of GnRH in your hormonal cascade — it's the signal that tells your brain to start producing reproductive hormones. Kisspeptin-10 triggers a rapid surge in LH and testosterone within hours of injection. Currently in clinical trials for fertility treatment and has potential as a more targeted alternative to GnRH analogs.

Commonly-researched dose ranges

Kisspeptin-10 is commonly researched at 50–500 mcg, pulsatile — 2–3x/week, by SubQ injection. These are reference ranges from the literature and community use, not a prescription.

Half-life

Estimated half-life: ~30 min. See how it accumulates in the half-life calculator.

Safety & interactions

Commonly reported effects: limited human data, lh/testosterone surge after dosing, potential mood effects, injection site reaction. Discuss with your clinician.

Open the full Kisspeptin-10 guide (needs JavaScript). PepVault is a private research and tracking tool, not medical advice.