Melanotan II dose guide

A peptide dosage chart, one peptide at a time: its dose range, how often it’s taken, a typical run and the units on your syringe. All 69 peptides in the PepVault library.

A community reference, not medical advice. Each range is what has been studied or is commonly run, never a dose for you.

Melanotan II dosage

A broad-spectrum melanocortin agonist originally developed for sunless tanning. MT-2 stimulates melanocytes to produce melanin (it works without sun; UV exposure speeds and deepens the tan), increases libido through central nervous system pathways, and can reduce appetite. PT-141 is a close analog, developed for sexual function after MT-2 caused erections in trials. Commonly reported: nausea and facial flushing after the first doses, easing with continued use; a fast, deep tan with freckles and moles visibly darkening; and spontaneous erections, frequent yawning and reduced appetite. Monitor moles carefully — it darkens all pigmented skin, and FDA cites melanoma reports.

Dose range
250–500 mcg (research range). Studied in research — not a recommendation.
How often
Daily: Loading: 250mcg daily for 1-2 weeks. Maintenance: 250-500mcg 2-3x/week or as needed.
A typical run
Loading 1–2 weeks, then maintenance ongoing. Loading phase until desired tan achieved, then reduce to maintenance. Sun or UV exposure enhances tanning effect.
How it’s taken
Vial: SubQ injection
Evidence
Emerging: Primarily preclinical / limited human data
Half-life
Unknown in humans

Melanotan II on your syringe

With a 5 mg vial and 2 mL of water (2.5 mg in every mL), on a 0.3 mL (30-unit) U-100 insulin syringe: the low end, 250 mcg, is 10 units; and the high end, 500 mcg, is 20 units. 20 doses in the vial at the low end. All U-100: 100 units to the mL. A U-40 syringe reads differently.

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A community reference, not medical advice. Each range is what has been studied or is commonly run, never a dose for you.