Glutathione dose guide

Glutathione dosage

Glutathione is the antioxidant every cell makes for itself, a three-amino-acid peptide that mops up peroxides and helps clear toxins, run by injection beside NAD+ and in "glow" protocols for a brighter skin tone. Injected, it is broken down within minutes, and its cysteine helps cells rebuild their own supply. Its human evidence is thin: small IV trials, oral skin-lightening trials with modest results, and none of SubQ or IM injection. Commonly reported: stinging at the injection site, and for some a brighter, more even skin tone over weeks; many notice nothing they can feel.

Dose range

100–600 mg (research range). Studied in research — not a recommendation.

How often

Daily: Daily or EOD

A typical run

Ongoing or in blocks. Community use runs from daily low doses to a few larger doses a week, often in blocks alongside NAD+; no study has tested an injected schedule. Swallowed glutathione is mostly broken down in the gut: a single 3 g dose didn't raise blood levels, though 6 months of daily 1,000 mg capsules raised body stores by 30–35%.

How it’s taken

Vial: SubQ injection, IM injection, IV infusion

Evidence

Emerging: Primarily preclinical / limited human data

Half-life

~14 min (measured in people after an IV infusion; never measured after SubQ or IM injection)

Glutathione on your syringe

With a 10 mg vial and 2 mL of water (5 mg in every mL), on a 1 mL (100-unit) U-100 insulin syringe: the low end, 100 mg, needs more than this vial holds; and the high end, 600 mg, needs more than this vial holds. All U-100: 100 units to the mL. A U-40 syringe reads differently.

Glutathione in the peptide libraryThe Dose Guide: every peptide

More longevity peptides

• MOTS-c 5–10 mg
• NAD+ 50–100 mg
• Epitalon 5–10 mg
• Humanin 2–4 mg
• FOXO4-DRI 1–2 mg
• SS-31 2–4 mg
• Pinealon 100–200 mcg
• Vesugen No reference dose
• Klotho 0.01–0.1 mg
• NMN 250–1000 mg
• SNAP-8 3–10%
• DSIP 200–400 mcg

A community reference, not medical advice. Each range is what has been studied or is commonly run, never a dose for you.