MK-677 — dosage, half-life & reference guide

Growth hormone peptide · also known as Ibutamoren, Nutrobal, MK677, Ibutamoren Mesylate

Not actually a peptide — it's a small molecule you take orally that mimics ghrelin to stimulate GH release. The convenience of a daily pill instead of injections makes it popular, but expect significant appetite increase and water retention. The 24-hour half-life means steady GH elevation from once-daily dosing.

Commonly-researched dose ranges

MK-677 is commonly researched at 10–25 mg, daily, before bed, by Oral. These are reference ranges from the literature and community use, not a prescription.

Half-life

Estimated half-life: ~24 hours (oral). See how it accumulates in the half-life calculator.

Safety & interactions

Commonly reported effects: increased appetite, water retention, lethargy, elevated fasting glucose, vivid dreams, carpal tunnel symptoms. Discuss with your clinician.

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