Compared side by side
CJC-1295 no DAC vs ipamorelin: how they differ
Reviewed How we check the library
The short answer
They raise growth hormone through different receptors: CJC-1295 no DAC is a GHRH analogue that amplifies each GH pulse, and ipamorelin is a ghrelin receptor agonist that triggers it, without raising cortisol in animal studies. That split is why they’re almost always stacked: together they release more GH than either alone. Both are typically taken 2–3 times a day.
Side by side
| Compared | CJC-1295 no DAC | Ipamorelin |
|---|---|---|
| Category | Growth hormone | Growth hormone |
| Also known as | Modified GRF 1-29, Mod GRF 1-29, CJC-1295 without DAC | IPAM |
| What it is | The shorter-acting version of CJC-1295, meant to give sharp, pulse-like GH release. | Considered the 'cleanest' growth hormone stimulator: in animal studies it triggers the pituitary to release GH without raising cortisol, a side effect common with other GH peptides. |
| How it works | GHRH analogue without the DAC modification. Its half-life in people hasn't been measured (native GHRH lasts minutes), and the short action gives pulse-like GH release. Usually stacked with Ipamorelin to mimic natural GH secretion patterns. | Selective growth hormone secretagogue and ghrelin receptor agonist. In animal studies it released GH without raising cortisol or ACTH, and users report milder hunger than with GHRP-6. Considered one of the cleanest GH pulses available. |
| Commonly reported | A flush or head rush within minutes of injecting, deeper sleep and vivid dreams early on, and mild water retention over the weeks. The no-DAC form itself has no published human studies. | Deeper sleep and vivid dreams first, then better recovery, skin quality and gradual body-composition changes, with milder hunger than GHRP-6. Its human data are a small GH study and phase 2 trials in surgical patients; it was never approved. |
| Studied range | Research range: 100–200 mcg. Studied in research — not a recommendation. | Research range: 200–300 mcg, starting dose 200 mcg. Studied in research — not a recommendation. |
| How often | 2–3x daily | 2–3x daily, best fasted or before bed |
| Half-life | ~30 min (community estimate; not measured in people: sermorelin, the unmodified 1-29 chain, lasts 11–12 minutes) | ~2 hours (measured in healthy men, given IV) |
| Route | SubQ injection | SubQ injection, IM injection |
| Typical run | 8–12 weeks typical. Usually stacked with Ipamorelin; cycle both together. | Commonly 8–12 weeks on, 4 weeks off to avoid receptor desensitisation. Some run longer with breaks. |
| Evidence | Moderate: animal studies + some human data | Moderate: animal studies + some human data |
| Common side effects | Water retention, headache, flushing, injection site pain | Headache, flushing, nausea, water retention, numbness/tingling |
- Category
- CJC-1295 no DACGrowth hormone
- IpamorelinGrowth hormone
- Also known as
- CJC-1295 no DACModified GRF 1-29, Mod GRF 1-29, CJC-1295 without DAC
- IpamorelinIPAM
- What it is
- CJC-1295 no DACThe shorter-acting version of CJC-1295, meant to give sharp, pulse-like GH release.
- IpamorelinConsidered the 'cleanest' growth hormone stimulator: in animal studies it triggers the pituitary to release GH without raising cortisol, a side effect common with other GH peptides.
- How it works
- CJC-1295 no DACGHRH analogue without the DAC modification. Its half-life in people hasn't been measured (native GHRH lasts minutes), and the short action gives pulse-like GH release. Usually stacked with Ipamorelin to mimic natural GH secretion patterns.
- IpamorelinSelective growth hormone secretagogue and ghrelin receptor agonist. In animal studies it released GH without raising cortisol or ACTH, and users report milder hunger than with GHRP-6. Considered one of the cleanest GH pulses available.
- Commonly reported
- CJC-1295 no DACA flush or head rush within minutes of injecting, deeper sleep and vivid dreams early on, and mild water retention over the weeks. The no-DAC form itself has no published human studies.
- IpamorelinDeeper sleep and vivid dreams first, then better recovery, skin quality and gradual body-composition changes, with milder hunger than GHRP-6. Its human data are a small GH study and phase 2 trials in surgical patients; it was never approved.
- Studied range
- CJC-1295 no DACResearch range: 100–200 mcg. Studied in research — not a recommendation.
- IpamorelinResearch range: 200–300 mcg, starting dose 200 mcg. Studied in research — not a recommendation.
- How often
- CJC-1295 no DAC2–3x daily
- Ipamorelin2–3x daily, best fasted or before bed
- Half-life
- CJC-1295 no DAC~30 min (community estimate; not measured in people: sermorelin, the unmodified 1-29 chain, lasts 11–12 minutes)
- Ipamorelin~2 hours (measured in healthy men, given IV)
- Route
- CJC-1295 no DACSubQ injection
- IpamorelinSubQ injection, IM injection
- Typical run
- CJC-1295 no DAC8–12 weeks typical. Usually stacked with Ipamorelin; cycle both together.
- IpamorelinCommonly 8–12 weeks on, 4 weeks off to avoid receptor desensitisation. Some run longer with breaks.
- Evidence
- CJC-1295 no DACModerate: animal studies + some human data
- IpamorelinModerate: animal studies + some human data
- Common side effects
- CJC-1295 no DACWater retention, headache, flushing, injection site pain
- IpamorelinHeadache, flushing, nausea, water retention, numbness/tingling
Typical run: Community practice — opinions vary. Not a clinical recommendation.
Week by week
Each entry’s cards by day window, as the compound pages show them. Day 1 is the day you start it.
CJC-1295 no DAC
- Day 1–14 Sleep usually moves first
- Day 14–28 Recovery is quicker, skin looks better
- Day 28–56 Body composition starts shifting
- Day 56–84 Cycle endpoint
Ipamorelin
- Day 1–14 Sleep is deepening
- Day 14–28 Recovery is noticeably faster
- Day 28–56 Body composition shifts showing up
- Day 56–84 Cycle-end + planned break
Together or one or the other
CJC-1295 no DAC and ipamorelin are a common stack: each lists the other among its common stacks, and they’re together in the GH Pulse + Repair and CJC-1295 + Ipamorelin stacks.
- GH Pulse + Repair: Body composition, GH optimization & recovery (CJC-1295 no DAC, Ipamorelin and BPC-157).
- CJC-1295 + Ipamorelin: Classic GH pulse stack — CJC-1295 no DAC + Ipamorelin (CJC-1295 no DAC and Ipamorelin).
Community · CJC-1295 no DAC
The core GH stack
The foundational GH stack: CJC-1295 amplifies each GH pulse and ipamorelin triggers it without raising cortisol (in animal studies), so together they give a larger GH response than either alone. Commonly reported: deeper sleep and better recovery than either alone.
Questions people ask
How long do CJC-1295 no DAC and ipamorelin last?
The half-life of CJC-1295 no DAC is ~30 min (community estimate; not measured in people: sermorelin, the unmodified 1-29 chain, lasts 11–12 minutes). The half-life of ipamorelin is ~2 hours (measured in healthy men, given IV).
How often are CJC-1295 no DAC and ipamorelin taken?
CJC-1295 no DAC: 2–3x daily. Route: SubQ injection. Ipamorelin: 2–3x daily, best fasted or before bed. Routes: SubQ injection, IM injection.
How are CJC-1295 no DAC and ipamorelin dosed in research?
The research range for CJC-1295 no DAC is 100–200 mcg. The research range for ipamorelin is 200–300 mcg, with a 200 mcg starting dose. Studied in research — not a recommendation.
What are the common side effects of CJC-1295 no DAC and ipamorelin?
For CJC-1295 no DAC, the library lists: water retention, headache, flushing, injection site pain. For ipamorelin: headache, flushing, nausea, water retention, numbness/tingling.
Are CJC-1295 no DAC and ipamorelin taken together?
CJC-1295 no DAC and ipamorelin are a common stack: each lists the other among its common stacks, and they’re together in the GH Pulse + Repair and CJC-1295 + Ipamorelin stacks. The foundational GH stack: CJC-1295 amplifies each GH pulse and ipamorelin triggers it without raising cortisol (in animal studies), so together they give a larger GH response than either alone. Commonly reported: deeper sleep and better recovery than either alone.
Each one in full
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Log every dose of CJC-1295 no DAC or ipamorelin, with reminders on your schedule. 7 days free on the yearly plan for new subscribers.
