# CJC-1295 no DAC vs Ipamorelin: How They Differ | PepVault

Source: https://pepvault.app/peptides/compare/cjc-1295-no-dac-vs-ipamorelin

Last updated: 2026-10-12

[Library](https://pepvault.app/peptides) [Comparisons](https://pepvault.app/peptides/compare) CJC-1295 no DAC vs Ipamorelin

Compared side by side

# CJC-1295 no DAC vs ipamorelin: how they differ

Reviewed October 2026 [How we check the library](https://pepvault.app/about#library)

## The short answer

They raise growth hormone through different receptors: CJC-1295 no DAC is a GHRH analogue that amplifies each GH pulse, and ipamorelin is a ghrelin receptor agonist that triggers it, without raising cortisol in animal studies. That split is why they’re almost always stacked: together they release more GH than either alone. Both are typically taken 2–3 times a day.

## Side by side

| Compared | [CJC-1295 no DAC](https://pepvault.app/peptides/cjc-1295-no-dac) | [Ipamorelin](https://pepvault.app/peptides/ipamorelin) |
| --- | --- | --- |
| Category | Growth hormone | Growth hormone |
| Also known as | Modified GRF 1-29, Mod GRF 1-29, CJC-1295 without DAC | IPAM |
| What it is | The shorter-acting version of CJC-1295, meant to give sharp, pulse-like GH release. | Considered the 'cleanest' growth hormone stimulator: in animal studies it triggers the pituitary to release GH without raising cortisol, a side effect common with other GH peptides. |
| How it works | GHRH analogue without the DAC modification. Its half-life in people hasn't been measured (native GHRH lasts minutes), and the short action gives pulse-like GH release. Usually stacked with Ipamorelin to mimic natural GH secretion patterns. | Selective growth hormone secretagogue and ghrelin receptor agonist. In animal studies it released GH without raising cortisol or ACTH, and users report milder hunger than with GHRP-6. Considered one of the cleanest GH pulses available. |
| Commonly reported | A flush or head rush within minutes of injecting, deeper sleep and vivid dreams early on, and mild water retention over the weeks. The no-DAC form itself has no published human studies. | Deeper sleep and vivid dreams first, then better recovery, skin quality and gradual body-composition changes, with milder hunger than GHRP-6. Its human data are a small GH study and phase 2 trials in surgical patients; it was never approved. |
| Studied range | Research range: 100–200 mcg. Studied in research — not a recommendation. | Research range: 200–300 mcg, starting dose 200 mcg. Studied in research — not a recommendation. |
| How often | 2–3x daily | 2–3x daily, best fasted or before bed |
| Half-life | ~30 min (community estimate; not measured in people: sermorelin, the unmodified 1-29 chain, lasts 11–12 minutes) | ~2 hours (measured in healthy men, given IV) |
| Route | SubQ injection | SubQ injection, IM injection |
| Typical run | 8–12 weeks typical. Usually stacked with Ipamorelin; cycle both together. | Commonly 8–12 weeks on, 4 weeks off to avoid receptor desensitisation. Some run longer with breaks. |
| Evidence | Moderate: animal studies + some human data | Moderate: animal studies + some human data |
| Common side effects | Water retention, headache, flushing, injection site pain | Headache, flushing, nausea, water retention, numbness/tingling |

Typical run: Community practice — opinions vary. Not a clinical recommendation.

## Week by week

Each entry’s cards by day window, as the compound pages show them. Day 1 is the day you start it.

### CJC-1295 no DAC

- Day 1–14 Sleep usually moves first
- Day 14–28 Recovery is quicker, skin looks better
- Day 28–56 Body composition starts shifting
- Day 56–84 Cycle endpoint

[Every card for CJC-1295 no DAC, with its sources](https://pepvault.app/peptides/cjc-1295-no-dac#weeks)

### Ipamorelin

- Day 1–14 Sleep is deepening
- Day 14–28 Recovery is noticeably faster
- Day 28–56 Body composition shifts showing up
- Day 56–84 Cycle-end + planned break

[Every card for ipamorelin, with its sources](https://pepvault.app/peptides/ipamorelin#weeks)

## Together or one or the other

CJC-1295 no DAC and ipamorelin are a common stack: each lists the other among its common stacks, and they’re together in the GH Pulse + Repair and CJC-1295 + Ipamorelin stacks.

- **GH Pulse + Repair**: Body composition, GH optimization & recovery (CJC-1295 no DAC, Ipamorelin and BPC-157).
- **CJC-1295 + Ipamorelin**: Classic GH pulse stack — CJC-1295 no DAC + Ipamorelin (CJC-1295 no DAC and Ipamorelin).

Community · CJC-1295 no DAC

### The core GH stack

The foundational GH stack: CJC-1295 amplifies each GH pulse and ipamorelin triggers it without raising cortisol (in animal studies), so together they give a larger GH response than either alone. Commonly reported: deeper sleep and better recovery than either alone.

## Questions people ask

### How long do CJC-1295 no DAC and ipamorelin last?

The half-life of CJC-1295 no DAC is ~30 min (community estimate; not measured in people: sermorelin, the unmodified 1-29 chain, lasts 11–12 minutes). The half-life of ipamorelin is ~2 hours (measured in healthy men, given IV).

### How often are CJC-1295 no DAC and ipamorelin taken?

CJC-1295 no DAC: 2–3x daily. Route: SubQ injection. Ipamorelin: 2–3x daily, best fasted or before bed. Routes: SubQ injection, IM injection.

### How are CJC-1295 no DAC and ipamorelin dosed in research?

The research range for CJC-1295 no DAC is 100–200 mcg. The research range for ipamorelin is 200–300 mcg, with a 200 mcg starting dose. Studied in research — not a recommendation.

### What are the common side effects of CJC-1295 no DAC and ipamorelin?

For CJC-1295 no DAC, the library lists: water retention, headache, flushing, injection site pain. For ipamorelin: headache, flushing, nausea, water retention, numbness/tingling.

### Are CJC-1295 no DAC and ipamorelin taken together?

CJC-1295 no DAC and ipamorelin are a common stack: each lists the other among its common stacks, and they’re together in the GH Pulse + Repair and CJC-1295 + Ipamorelin stacks. The foundational GH stack: CJC-1295 amplifies each GH pulse and ipamorelin triggers it without raising cortisol (in animal studies), so together they give a larger GH response than either alone. Commonly reported: deeper sleep and better recovery than either alone.

## Each one in full

- [CJC-1295 no DAC: dosage, half-life & reference guide](https://pepvault.app/peptides/cjc-1295-no-dac)
- [Ipamorelin: dosage, half-life & reference guide](https://pepvault.app/peptides/ipamorelin)
- [CJC-1295 no DAC dose guide](https://pepvault.app/lab/dosage/cjc-1295-no-dac)
- [Ipamorelin dose guide](https://pepvault.app/lab/dosage/ipamorelin)

PepVault for iPhone

## Track either one in PepVault

Log every dose of CJC-1295 no DAC or ipamorelin, with reminders on your schedule. 7 days free on the yearly plan for new subscribers.

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## More comparisons

- [All peptide comparisons](https://pepvault.app/peptides/compare)
- [CJC-1295 with DAC vs CJC-1295 no DAC](https://pepvault.app/peptides/compare/cjc-1295-with-dac-vs-cjc-1295-no-dac)
- [Ipamorelin vs Sermorelin](https://pepvault.app/peptides/compare/ipamorelin-vs-sermorelin)
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## The library

- [The peptide reference library](https://pepvault.app/peptides)
- [Growth hormone peptides](https://pepvault.app/peptides#growth-hormone)

## Free tools

- [The Dose Guide](https://pepvault.app/lab/dosage)
- [Half-life & active level](https://pepvault.app/tools/peptide-half-life-calculator)
- [Reconstitution calculator](https://pepvault.app/tools/reconstitution-calculator)

PepVault is a research and tracking resource, not medical advice. Ranges are what studies used, never a dose for you. Brand names are trademarks of their owners; PepVault is independent of them.

PepVault is a private research and tracking tool, not medical advice. The information here is reference material from published literature and community use — always verify it and discuss any protocol with a qualified clinician before changing it.

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